Category: pharma

  • Pfizer says U.S. court invalidates Celebrex patent; generics loom — Reuters

    Pfizer — U.S. court invalidates Celebrex patent; generics loom | Reuters:

    Ouch!:-(

    Knocking the block of of the buster.

    Pfizer is taking a big hit with this court ruling against Celebrex patent. Surprisingly, the stock price, not so much so. Almost not even a jitter as it stays around $32 per share.

    That’s $3B in annual sales with $2B in the US (relevant to the US court ruling, obviously).

    IF the company repeats its $51B in sales from last year (revenues have been dropping over the last 3 years) then that represents about 4% to 6% of the companies sales. But it has to represent a huge hit to the bottom line, let’s say 8% to 15%. (It doesn’t take much to milk the cash cows; it does however, take a lot of money to invent the cow, clone it, raise the herd to maturity, and then milk each cow for all she’s got for about 20 years.)

    It look like the patent would have expired in 2015 anyway, so there would be generics already sitting on the sidelines (or the storefront in other countries).

    This must have been totally expected. It is hard to imaging a $204B company (based on market cap) that doesn’t take a serious tumble when one of its blockbuster products takes a hit.

    It is blockbuster patents in Big Pharma going off patent like this that contribute to the slowing of Healthcare spending. That’s right. Healthcare spending has only been increasing at about 4% over the last couple years. A big part of that is the patent cliff for big pharma drugs.

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  • Top 15 drug patent losses for 2013 – … And Viagra…

    Top 15 drug patent losses for 2013 – FiercePharma:

    In the usual search of the BIG patents that are about to drop off the cliff, it is always fun to see what comes up.

    This is a great assessment of the 2013 Patent Cliff.

    Wanna see what’s in store for the the next 4-5 years check out this report and forecast for pharma patents through 2018 by EvaluatePharma: http://www.evaluatepharma.com/worldpreview2018.aspx

    Just reviewing the past couple years you will see Plavix and Lipitor going off patent with more than $5B in annual sales. Wow. Look at this from 2011: The 10 Biggest-Selling Drugs That Are About to Lose Their Patent – DailyFinance: “Plavix”

    But I got tripped up in the Viagra and its patent status. Check out this article from the BBC: http://www.bbc.co.uk/news/business-20258639

    Pfizer lost its Viagra patent in Canada. The Supreme court there was unforgiving in the approach that was taken in the patent to mention everything including the kitchen sink, not primarily focus on the only active ingredient  The court thought that this was a poor attempt at “gaming” the patent process and seemed rather less than entertained. Ouch!.

    In Canada the patent was due to expire in 2014 anyway.  Seems that the main patent in the US will go public domain in 2018.

    ‘via Blog this’